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Stanford breast cancer cancer cell

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Part of a series on tiny answers to biology's biggest questions. Ovijit Chaudhuri and his lab are studying how mechanical properties of breast tissue influence tumor cells. Image credit: Courtesy Department of Mechanical Engineering. One of the most puzzling questions in breast cancer research is why some tumors stay put, while rogue cells from others break free and spread to surrounding tissues, the first step toward creating a more lethal disease. Curiously, one path to unraveling this mystery may lie in a field not usually associated with cancer research: mechanical engineering. By understanding that interplay better, he said, they may — one day — be able to develop better treatments for the women most at risk and ease the often-painful burden for the many others who currently undergo treatment but are less at risk.
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Cancer Clinical Trials

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Cancer (Stanford Encyclopedia of Philosophy)

Breast cancer is the most common cancer in women and about a quarter of a million new cases of breast cancer are diagnosed every year. In the past, breast cancer patients were prescribed the same blanket treatment. How can we describe these different cases? Researchers and clinicians have answered these questions by analyzing patient tumors using computational methods. Their data analysis has revealed the existence of new subtypes that benefit from therapies targeted specifically to their cancer, helping us refine our treatments and improve patient survival. In supervised learning , the computer sifts through data and finds particular patterns in the features of this data that separate the data into different groups or classes.
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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

Invasive lobular carcinoma of the breast. Cancers pose the greatest danger when they become invasive and then spread from their originating tissues throughout the body. Stanford researchers have discovered that breast cancer cells can push their way through the body to invade surrounding tissue.
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Stanford researchers have found that malignant breast cancer cells can extend protrusions known as invadopodia to dig escape tunnels through surrounding tissue, revealing a possible new target for therapies. Cancers pose the greatest danger when they become invasive and then spread from their originating tissues throughout the body. Stanford researchers have discovered that breast cancer cells can push their way through the body to invade surrounding tissue. Although scientists have long known that cells have a chemical means of breaking free, Stanford researchers have discovered that breast cancer cells can also physically push their way out of their normal confines to become invasive tumors. The work could point to new ways of preventing cancers from spreading.
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